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UNC1999 br Material and methods Clinical trial NCT
2019-08-26
Material and methods Clinical trial NCT00729612 (NCCN A-08) was a phase II trial of carboplatin and nab-paclitaxel in 63 patients with advanced or metastatic NSCLC conducted at The Ohio State University with the support of the National Comprehensive Cancer Network (NCCN) Oncology Research Program
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The final issue identified by our review is that
2019-08-16
The final issue identified by our review is that the central reason for the limited availability of official cervical cancer mortality data noted by IARC for the most recent reported HCMC cancer registry (2009–2012), is that death certificates have not been used to identify the cause of death in Vie
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It is also possible that differences in participation
2019-08-16
It is also possible that differences in participation in CCS according to α-CEHC status might be more pronounced among overweight and obese women than among women with lower BMI. Indeed, different explanations have been proposed to explain why obese women delay CCS, such as poor self-esteem and
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Galactose 1-phosphate br Discussion All but one perfor
2019-08-16
Discussion All but one performance indicator from The Danish National Colorectal Cancer Screening Programme were well above the acceptable level and close to or just above the desirable level from the European Guidelines (Table 3). The remaining performance indicator (the inadequate FOBT rate) wa
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The variation in travel time to nearest surgical treatment c
2019-08-16
The variation in travel time to nearest surgical treatment centre was greater than that Pifithrin-α (PFTα) to radiotherapy centre (travel time to thoracic centre: median = 30 min, IQR [18–48], travel time to RT centre: median = 24 min, IQR [14–35]). Most thoracic surgery units and radiotherapy centr
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As in other regions the economic burden of skin cancer
2019-08-16
As in other regions, the economic burden of skin cancer in Portugal will probably continue to increase with the aging of the N-octanoyl-L-Homoserine lactone [[35], [36], [37]]. Additionally, treatment of skin cancer is changing, especially for advanced stages, with the introduction of new – but exp
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Introduction Little is known about the aetiology of
2019-08-11
Introduction Little is known about the aetiology of childhood cancers. Many studies targeted lifestyle factors or environmental pollutants as possible risk factors but with inconsistent results [1,2]. To date, a few genetic conditions, exposure to high-dose ionizing SCH 58261 and prior chemotherap
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CRC is the third most
2019-08-11
CRC is the third most common cancer type in Denmark, as well as worldwide [10], and the fourth most common cause of cancer death [11]. CRC accounts for 12.7% and 12.1%, respectively, of all cancer cases among Danish men and women [10]. Danish men have a total average intake of 1,134 g raw red and p
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br Transparency document br Introduction AMPA
2019-07-30
Transparency document Introduction AMPA receptors (AMPARs) are ionotropic glutamate receptors that mediate fast synaptic transmission in the central nervous system and modulate cognitive and motor function [1], [2], [3], [4], [5], [6], [7], [8], [9]. AMPARs are tetrameric heteromeric complexes
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BCI-121 In this study we showed that the expression and acti
2019-07-24
In this study we showed that the expression and activity of MMP-2 are upregulated in cardiac tissue during the chronic phase of T. cruzi infection. Such increase is detected in association with abundant inflammatory BCI-121 infiltrating the myocardium. More important, we found that the pleiotropic
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The mitochondrial aspartate glutamate carrier isoform AGC
2019-07-24
The mitochondrial aspartate-glutamate carrier isoform 1 (AGC1) belongs to the mitochondrial carrier family: proteins localized in the inner membrane of mitochondria which catalyze the translocation of a variety of metabolites, nucleotides and cofactors across the membrane thus providing a link betwe
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Supported by Queensland Cancer Council Project
2019-07-24
Supported by: Queensland Cancer Council Project Grant (APP1123436, LH) and James Cook Development Grant (94066) 2016-17 (LH). Transparency document Introduction Glucocorticoids, produced in the adrenal glands upon activation of the hypothalamic-pituitary-adrenal axis (HPA axis), are essential
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br Conflicts of interest br Transparency document br Acknowl
2019-07-08
Conflicts of interest Transparency document Acknowledgements N. Pradhan and S. Parbin are thankful to DST, Govt. of India for providing INSPIRE fellowship. L. Das is thankful to SERB-DST, Govt. of India for providing National Postdoctoral Fellowship (Grant Number-PDF/2015/000757). S. Kar, D
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A hallmark of liver fibrosis is the
2019-07-08
A hallmark of liver fibrosis is the activation of HSCs, which serve as major producer of fibrogenic extracellular matrix [33]. Damaged cholangiocytes express a number of SASPs (e.g., TGF-β1) [34], profibrogenic and chemotactic proteins, attracting inflammatory KX2-391 and activating HSCs by paracri
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The following are the supplementary data
2019-07-08
The following are the supplementary data related to this article. Transparency document Introduction Pathological cardiac hypertrophy induced by hypertension or other stimuli is a leading cause of morbidity and mortality worldwide [1]. During the development of cardiac hypertrophy, the heart