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br Discussion br PEPT is an attractive molecular target for
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4. Discussion PEPT1 is an attractive molecular target for the drug delivery into tumor cells in terms of cancer treatment and diagnosis. In normal tissues, the predominant expression of PEPT1 protein is restricted to the luminal membrane of enterocytes in the small intestine with lower level of
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br Patients and Samples Primary Cell Culture br
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Patients and Samples (Primary Cell Culture) This study was conducted according to the “REporting recommen-dations for tumor MARKer prognostic studies” [43]. To establish primary, patient-derived ovarian cancer cell cultures, we analyzed samples from patients undergoing surgical resection betwee
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Ahsan N et al Comparative
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Ahsan, N., et al., 2018. Comparative effects of Bisphenol S and Bisphenol A on the development of female reproductive system in rats; a neonatal exposure study. Chemosphere 197, 336e343. Aiba, T., et al., 2018. Does the prenatal bisphenol A exposure alter DNA methylation levels in the mouse hippo
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br a Guangdong Provincial Key Laboratory of Malignant
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a Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Thoracic Surgery, Sun yat-sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China b Department of Thoracic Surgery, Cancer Center of Guangzhou Medical University, Guangzhou 51000
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Materials Science Engineering C br Preparation of AgNPS
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Materials Science & Engineering C 102 (2019) 254–263 2.3. Preparation of AgNPS About 1 mM silver nitrate (AgNO3 Sigma- Aldrich) solution was added drop wise to the bacterial supernatant with constant stirring by using glass rod. After this, the solution was kept on a shaker for 24 h at 125
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br In light of this information we were
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In light of this information, we were interested in clarifying if hy-droxycyperaquinone could be a new proteasome inhibitor. To this end, we have assessed the ability of hydroxycyperaquinone to inhibit the chymotrypsin-like activity of 20S subunit of the 26S proteasome. As shown in Fig. 8, hydroxy
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Pepstatin-A br Resveratrol trihydroxy trans stilbene is
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Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is one of the natural polyphenols produced by several plants, including grapes, blueberries, raspberries as an immune response against to injury or pathogen attack (Frémont, 2001). By regulating different molecular targets, it has been shown to involve
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br Table br Results from the multiple linear
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Table 4 Results from the multiple linear regression models of the relationship between attachment anxiety, attachment avoidance, demoralization, and depression (N = 382). Demoralization Depression Predictors βa 95% CI p βa 95% CI p Attachment anxiety subscale Model 2a Mo
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G 418 br Fig Wheat bracts and
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Fig. 1. Wheat bracts and the siliceous prickles on their surfaces observed by scanning electron microscopy and light microscopy. A) Wheat seed and bracts including palea, lemma, and glume. B) Single prickle (pr) on the surface of the glume (Source: Hodson and Sangster, 1989). C) Abundant silicifie
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br in silico analysis br According
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5.3. in silico analysis According to RNAsnp prediction, which predicts the effects of SNPs on the secondary structure of RNA, there is an alteration in the sec-ondary structure of WRAP53 RNA by rs2287499 but there was no change in p53 RNA by rs1042522 (Fig. 2). Results from Fathmm, which predict
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BsmI rs SNPs have individually demonstrated
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BsmI-rs1544410 SNPs have individually demonstrated weak or nonsignificant statistical effects on BC susceptibility in different studies.23-29 However, the influence of their combination and SNP-SNP interactions on BC risk is not known. Therefore, this study investigated the potential SNP-SNP i
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br Scarabelli C Gallo A Zarrelli A
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30. Scarabelli C, Gallo A, Zarrelli A, Visentin C, Campagnutta E. Systematic pelvic and para-aortic lymphadenectomy dur-ing cytoreductive surgery in advanced ovarian cancer: potential benefit on survival. Gynecol Oncol. 1995;56:328–337. 33. Li X, Xing H, Li L, et al. Clinical significance of pa
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br Fig Fluorescence emission spectra of A D C B
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Fig. 5. Fluorescence emission spectra of (A, D) C3, (B, E) C5 and (C, F) C8 with increasing concentration of AT11 G4 (top) or AT11-B0 G4 (bottom). Insets: fraction of ligand bound plots fitted to the Hill saturation binding model. Spectra acquired in 20 mM potassium phosphate buffer containing 65 m
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br Clinical Genitourinary Cancer Vol No Elsevier Inc All rig
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Clinical Genitourinary Cancer, Vol. 17, No. 3, 183-90 ª 2019 Elsevier Inc. All rights reserved. Keywords: Gas chromatography-mass spectrometry, Metabolomics, Nonparametric statistics, Prostatic neoplasms, Stir bar sorptive extraction 1Department of Chemistry and Biochemistry 2Department of M
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br Cytosolic lactate dehydrogenase LDH is used
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Cytosolic lactate dehydrogenase (LDH) is used as a marker of cell death for in vitro models since LDH is released through the compro-mised cell membrane. The finding that MDA-MB-231 cells treated with BthTX-II display a decreased LDH activity, may justify the presence of necrotic or late apoptotic