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br Introduction br Cancer ranks as the leading cause of
2020-08-30
1. Introduction Cancer ranks as the leading cause of mortality in Japan. In 2017, around 30% of deaths have been attributed to cancer, making it a major health problem [1]. Approximately 90% of deaths are caused by cancer invasion and metastasis. During cancer progression, cancer 1821-12-1 des
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br Neutrophils but not monocytes or macrophages were
2020-08-30
Neutrophils but not monocytes or macrophages were essential to deter tumor-infiltrating bacteria and dampen CRC promoting inflammation. Neutrophils represent an important component of the tumor microenvironment, where they can be immunosuppressive as a form of myeloid derived suppressor Ceruletide
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br Liposome preparation br The nomenclature and lipid
2020-08-30
2.2. Liposome preparation The nomenclature and lipid compositions of the liposomes used in the study are given in Table 1. The liposomes were prepared via thin film hydration and extrusion method (Nikpoor et al., 2015). Briefly, appropriate amounts of phospholipids were added to a round-bottome
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br Fig CDH is significantly
2020-08-30
Fig. 1. CDH17 is significantly increased in gastric cancer. (a) High expression of CDH17 observed in GC via IHC (400×). (b) Moderate expression of CDH17 observed in GC via IHC (400×). (c) Low expression of CDH17 observed in GC via IHC (400×). (d) Negative CDH17 expression in para-carcinoma tissue
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br Cathepsin D conjugated peptides were self assembled into
2020-08-30
Cathepsin D-conjugated peptides were self-assembled into nano-particles with the help of gelatin to bypass early nonspecific dissolution as well as off-target Dox release and is useful for optical imaging in animal models [184]. Cathepsin D is an enzyme for breast cancer cell se-cretion, which got
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br d ejection ventriculaire gauche FEVG finale L
2020-08-28
d’ejection ventriculaire gauche (FEVG) finale. L’analyse de la cova- riance (ANCOVA) a ete utilisee pour evaluer la relation entre l’ex-position à la statine et la FEVG finale. Un modèle de regression logistique a ete elabore pour evaluer la relation entre l’exposition à la statine et la
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SCR7 br Discussion br This study
2020-08-28
Discussion This study shows an association between individual cardiac dose distributions and subclinical systolic dysfunction of the LV after RT for BC. The subclinical marker, GLS of the LV, was most associated with the maximum dose to the LMCA. Notably, all DVH parameters that were selected f
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br Introduction br Lack of physical activity is
2020-08-28
1. Introduction Lack of physical activity is a known risk factor for various co-mor-bidities, including cancers of the colon, postmenopausal breast and corpus uteri [1–7]. Physical activity is defined as any movement of the skeletal muscles that increases 2097381-85-4 expenditure above the res
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br Introduction br Glioblastoma GBM is the most malignant
2020-08-28
1. Introduction Glioblastoma (GBM) is the most malignant primary human brain cancer, and improved treatments for this disease are needed [1–7]. Increasing evidence has shown that a subset of GBM cells have stem-like properties and the ability to initiate tumors [8,9]. These cells, being resista
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br Conclusions br We have demonstrated the applicability
2020-08-28
5. Conclusions We have demonstrated the applicability of the multiplicative (re-lative) risk model to data from glycidol carcinogenicity studies. A good agreement between observed and predicted tumor incidence was shown in glycidol-exposed mice and rats, indicating a relative risk coefficient p
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Gly-Pro-pNA br studies mutations in a gene have also been pr
2020-08-28
studies, mutations in a gene have also been proposed to be studied in a matrix as an input for a kernel test [45,46]. In this study, we proposed using a framework which utilizes a regression model to pre-select de-leterious genes, nsNMF to decompose the matrix, SVM to train a clas-sifier, and then
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br L induces apoptosis in a caspase
2020-08-28
3.2. L80 induces apoptosis in a caspase-dependent manner L80-induced apoptosis was evaluated by annexin V assay. A sig-nificant increase in early and late apoptotic LY-294002 in the presence of L80 (5–10 μM) was observed (p < 0.05, Fig. 2A). This effect was accom-panied by caspase-3 activation
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br However currently radiologists use single view
2020-08-18
113 However, currently radiologists use single view CAD article. 114 51 systems as a second reader for breast cancer diagnosis using 52 FFDM images [10]. These CAD systems have high false positive 2. Literature survey 53 (FP) and false negative (FN) rates because of varying s
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br Discussion br PEPT is an attractive molecular target for
2020-08-18
4. Discussion PEPT1 is an attractive molecular target for the drug delivery into tumor cells in terms of cancer treatment and diagnosis. In normal tissues, the predominant expression of PEPT1 protein is restricted to the luminal membrane of enterocytes in the small intestine with lower level of
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br Patients and Samples Primary Cell Culture br
2020-08-18
Patients and Samples (Primary Cell Culture) This study was conducted according to the “REporting recommen-dations for tumor MARKer prognostic studies” [43]. To establish primary, patient-derived ovarian cancer cell cultures, we analyzed samples from patients undergoing surgical resection betwee